Phrase of miRNAs into the embryonic gonad

Phrase of miRNAs into the embryonic gonad

Current research reports have >2009 ; Huang et al. 2010 ; Tripurani et al. 2010 ; Torley et al. 2011 ). Though there aren’t any cross-species studies that compare gonadal miRNA phrase habits at comparable time points, you will find sets of miRNAs which are commonly up-regulated in the gonads across different types. As an example, miRNA 101 (miR-101) is up-regulated within the testis of sheep, pig, and mouse (Yu 2005 ; Luo et al. 2010 ; Torley et al. 2011 ). Likewise, miR-202-5p is up-regulated in mouse and pig testes (Mishima et al. 2008 ; Luo et al. 2010 ). Nonetheless, you will find studies undermining the necessity of miRNAs during embryonic gonadal differentiation, including research on Dicer knockout embryos. Weiterlesen